Week Ten College Football 2021 Preview

College Football Week 10 - Auburn vs. Texas A&M
Zac Al-Khateeb. Getty Images.

Week Ten of the College Football season is here! This may be the weakest week of games all season, but that usually means a bunch of upsets will happen. Let’s dive in!

Here is your Week Ten College Football 2021 preview.

Week Ten College Football Top Matchups

No. 3 Michigan State at Purdue

  • Game Info: Saturday, 3:30 p.m. ET (ABC)
  • Prediction: Purdue 24, Michigan State 21

Michigan State is coming off a huge win against Michigan, then followed that up with a big move up in the Playoffs rankings to #3. So life is good if you are a spartan.

They are about to face a Boilmakers team that already upset one top team in Iowa, will they follow that up with another upset?

Purdue gives up a ton of yards on defense. It doesn’t allow a lot of points, though – it’s an odd team – but even so, this might be the exact type of fit for Purdue.

This isn’t a Drew Brees/Billy Dicken/Kyle Orton Basketball on Grass type of team. It plays games in the 20s – the Boilermakers have yet to play a game this year with a point total over 51.

Unlike Michigan State, Purdue doesn’t get hit with penalties – it gets flagged the fewest times in the Big Ten. The defense only gives up 314 yards per game and is great on third downs, and overall, it’s more about ball control than anything else.

So with this combination, I am calling the upset here, Purdue pulls another one out of their hat.

No. 13 Auburn at No. 14 Texas A&M

  • Game Info: Saturday, 3:30 p.m. ET (CBS)
  • Prediction: Texs A&M 31, Auburn 21

Texas A&M is finally rested after a bye.

They’ve had two weeks off after winning their last two games by a combined score of 79-28, and now it’s time to win a really, really big game again.

A&M still needs another Alabama loss – go Auburn – but it’ll grind its way out to a terrific win here to keep hopes of winning the SEC West alive.

Yes, Nix is playing well, and the offense is doing a great job, but the A&M defense will come up with a gem.

LSU at No. 2 Alabama

  • Game Info: Saturday, 7:00 p.m. ET (ESPN)
  • Prediction: Alabama 42, LSU 14

The LSU running game has been better, but I don’t think its better enough to pull off the upset here.

The 321 yards against the Gators were an aberration – the Tigers haven’t hit the 150-yard mark on the ground against anyone else.

The bigger problem is on the other side, with the run defense getting rumbled over way too easily. The Tigers allowed close to 800 yards over the last three games, and Alabama is going to keep that going by pounding away right away.

The banged up LSU secondary will have a rough time, and Bryce Young will have plenty of shots at big things down the field, but expect a steady dose of Brian Robinson throughout the first half should set the tone, and then everything will open up.

LSU will look and play like a fresh team for about 20 minutes. It’s going to bring the A effort, come up with a slew of quirky plays, and it’s going to be a fight for a while. But one Alabama scoring run later – helped by a few LSU offensive stalls – and this will all be over.

No. 4 Oregon at Washington

  • Game Info: Saturday, 7:30 p.m. ET (ABC)
  • Prediction: Oregon 32, Washington 29

The Oregon Ducks are no. 1 in the Pac-12 North division, but they are far from having secured that position, especially with the Washington State Cougars right behind them. Up ahead for the Ducks is a matchup against the Washington Huskies, who could tie the Ducks, record-wise in the conference if they can defeat Oregon at home this weekend. Check out our preview of this game below.

Oregon continues to move further away from its loss to the Stanford Cardinal on the road earlier this month. Since then, the Ducks have stitched together three wins in a row, including their 52-29 blowout victory over the Colorado Buffaloes in Eugene last Saturday. Quarterback Anthony Brown sizzled under center in that game, passing for 307 yards and three touchdowns with zero interceptions while running back Byron Cardwell went off with 127 rushing yards and a touchdown on just seven carries. Travis Dye added two rushing touchdowns.

Washington has also scored consecutive wins in its last two games. It defeated the going-nowhere Arizona Wildcats on the road on Oct. 22, 21-16, before taking care of business away from home in a 20-13 victory over the Stanford Cardinal on Oct .30. The Huskies hope that the success continues when they play their first game at Husky Stadium in quite a while. The last time Washington played at home was on Sep. 25, which was the Huskies defeated the California Golden Bears, 31-24 (OT).

Washington has played in five straight one-score games, while Oregon has won the last two meetings between the two by a combined total of seven points. So I suspect this one to be close but that Oregon holds on for a close one.

Other Week Ten College Football Contests

Missouri at No. 1 Georgia

  • Game Info: Thursday, 12:00 p.m. ET (ESPN)
  • Prediction: Georgia 52, Missouri 7

The Bulldogs are the top team in the first set of CFP rankings, and this is their largest spread to date this season. Georgia is 5-2 against the spread as a favorite this year, and Missouri has already suffered a 38-point loss to Tennessee. The Bulldogs have won seven in a row in the series. Bulldogs big here.

No. 5 Ohio State at Nebraska

  • Game Info: Satursday, 12:00 p.m. ET (Fox)
  • Prediction: Ohio State 49, Nebraska 21

The Huskers have suffered three straight one-score losses and are on the brink of another losing season under Scott Frost. The Buckeyes’ defense has improved, and the offense should clean up the red-zone issues it had against Penn State. That’s bad news for Nebraska. Ohio State has won the last two meetings by an average of 33 points per game. 

Liberty at No. 16 Ole Miss

  • Game Info: Saturday, 12:00 p.m. ET (SECN)
  • Prediction: Ole Miss 59, Liberty 38

Former Ole Miss coach Hugh Freeze is up against his old team, and that’s just one headline. The quarterback matchup between Matt Corral and Malik Willis will have NFL scouts’ attention. The over (68.5) is in play here too as this has the potential to be a high-scoring affair. I think Ole Miss wins comfortably though.

No. 12 Baylor at TCU

  • Game Info: Saturday, 3:30 p.m. ET (Fox)
  • Prediction: Baylor 28, TCU 14

TCU parted ways with longtime coach Gary Patterson this week, so it’s anybody’s guess what kind of frame of mind the Horned Frogs are in. Baylor continues to win with a punishing ground game that averages 233.9 rushing yards per game. The Bears also are 5-1 this year as a favorite.

Tulsa at No. 6 Cincinnati

  • Game Info: Saturday, 3:30 p.m. ET (ESPN2)
  • Prediction: Cincinnati 42, Tulsa 21

The Bearcats’ are being pressured to run up the score given their precarious playoff position, and they have failed to cover spreads of 20 points or more the last two weeks. Tulsa presents one of those “common opponent” chances. Ohio State beat the Golden Hurricane 41-20 earlier this season.

Navy at No. 10 Notre Dame

  • Game Info: Saturday, 3:30 p.m. ET (ESPN)
  • Prediction: Notre Dame 45, Navy 14

The Irish have won the last two meetings with the Midshipmen by 27 points per game. Navy has a losing record but has been playing teams tough this year with one-score losses against Houston, SMU and Cincinnati. Navy slows this one down a bit but Notre Dame should win easily.

No. 11 Oklahoma State at West Virginia

  • Game Info: Saturday, 3:30 p.m. ET (ESPN)
  • Prediction: OSU 28, West Virginia 21

This might be the trickiest game of the week. The Mountaineers have been up and down all year, and the Cowboys are trying to stay in the Big 12 championship hunt. Oklahoma State has won the last six meetings, however, and they do enough in the running game to escape Morgantown with a victory. 

Tennessee at No. 18 Kentucky

  • Game Info: Saturday, 3:30 p.m. ET (ESPN2)
  • Prediction: Kentucky 31, Tennessee 28

I am really tempted to take Tennessee here. The Volunteers had a bye week and have an offense that will test a Kentucky team coming off back-to-back road losses. The Wildcats, however, are 4-0 at home against FBS opponents and have covered in all of those games. 

No. 22 Iowa at Northwestern

  • Game Info: Saturday, 7:00 p.m. ET (BTN)
  • Prediction: Iowa 21, Northwestern 17

The Hawkeyes suffered back-to-back losses, but Northwestern has been in a tougher place. The Wildcats have been blown out in three of their last four games. Northwestern has won four of the last five meetings. At home, they find a way to hang around but ultimately fall.

Boise State at No. 25 Fresno State

  • Game Info: Saturday, 7:00 p.m. ET (CBSSN)
  • Prediction: Fresno State 34, Boise State 31

These Mountain West Conference championship game regulars meet in a series they have split in the last four meetings. Boise State has four losses by 10 points or less, and they have a chance to pull the upset on the road. Only this time, Fresno State’s Jake Haener comes through in the clutch. 

Indiana at No. 7 Michigan

  • Game Info: Saturday, 7:30 p.m. ET (Fox)
  • Prediction: Michigan 35, Indiana 20

Michigan is coming off a tough loss to Michigan State, but motivation won’t be required this week. The Hoosiers embarrassed the Wolverines 38-21 last season. Michigan is looking to get revenge here. Something to note, Indiana will be starting a true freshman, that could be a spark or a huge reason they lose here.

College Football – Upset Alert

No. 9 Wake Forest at North Carolina

  • Game Info: Saturday, 12:00 p.m. ET (TBD – ACCN or ABC)
  • Prediction: North Carolina 51, Wake Forest 48

This promises to be a shootout between Sam Hartman and Sam Howell. The home team has won the last six meetings, and I think that continues here with the North Carolina upset.

Should be another excellent week of College Football!

Follow us on Twitter!

Check out our shop!



  1. Pingback: CFP Top 25 Football Schedule Week 10 - Championship Sports Media

  2. Pingback: Week Ten College Football Final Word - Championship Sports Media

Leave a Reply

Follow our Twitter, Facebook, Instagram, Twitch, and YouTube Below

Copyright © 2015 Flex Mag Theme. Theme by MVP Themes, powered by Wordpress.

To Top
%d bloggers like this: